A-002 (Varespladib), a phospholipase A2inhibitor, reduces atherosclerosis in guinea pigs
نویسندگان
چکیده
منابع مشابه
A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs
BACKGROUND The association of elevated serum levels of secretory phospholipase A2 (sPLA2) in patients with cardiovascular disease and their presence in atherosclerotic lesions suggest the participation of sPLA2 enzymes in this disease. The presence of more advanced atherosclerotic lesions in mice that overexpress sPLA2 enzymes suggest their involvement in the atherosclerotic process. Therefore,...
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ژورنال
عنوان ژورنال: BMC Cardiovascular Disorders
سال: 2009
ISSN: 1471-2261
DOI: 10.1186/1471-2261-9-7